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Image Search Results
Journal: Cell reports
Article Title: Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
doi: 10.1016/j.celrep.2019.12.056
Figure Lengend Snippet: Figure 7. EZH2 Inhibition Impairs Metastasis in TNBC Subtype-Specific PDX Models (A) EZH2 and GATA3 expression of the METABRIC dataset of 347 breast cancer patients, available in cBioportal and grouped by Pietenpol TNBC subtypes. Data represent median ± interquartile range (Wilcox t test). (B) Quantitative analysis of the invasive potential of HCC1937 (BL-1), MDA-MB-468 (BL-1), BT-549 (M), CAL-120 (M), MDA-MB-453 (LAR), SUM185 (LAR), and CAL-148 (LAR) cell lines following treatment with vehicle or drug (5 mM GSK-126 for 5 days) and quantification of invasive cells of six distinct images in each replicate (n = 3) per group. The invasion of vehicle-treated cells was set at 1.
Article Snippet: Human breast cell lines MCF10A, MDA-MB-361, MCF7, MDA-MB-436, MDA-MB-231, BT-20,
Techniques: Inhibition, Expressing
Journal: Molecular Cancer
Article Title: Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase
doi: 10.1186/1476-4598-9-307
Figure Lengend Snippet: Identification of RON mRNA transcripts with alterations in the first IPT Unit in colon, breast, and pancreatic cancer cells.
Article Snippet: Human colon (HT-29, SW620, and SW837), breast (HCC-1937, MDA-MB231, T-47D, ZR-751, and MCF-7), and pancreatic (
Techniques: